分子量：Calculated MW: 109kDa/200kDa/201kDa/236kDa/238kDa
Observed MW: 238kDa

细胞定位：Chromosome, Cytoplasm, Nucleus matrix, cytoskeleton, spindle pole

稀释方法：WB 1:200 - 1:1000
IHC 1:50 - 1:100
IF 1:50 - 1:100

总结：This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.